Table 2 Association of pre-diagnostic inflammatory score (A) and the first PC (B) with breast cancer case/control.
Full Breast Cancer population | TtD ≤ 6 years* | TtD > 6 years* | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Model 1 | Model 1 + Behaviours | Model 1 + SEP | Model 1 + Hormonal | Fully adjusted model | Fully adjusted model | Fully adjusted model | ||||||||
β (SE) | P-value | β (SE) | P-value | β (SE) | P-value | β (SE) | P-value | β (SE) | P-value | β (SE) | P-value | β (SE) | P-value | |
(A) Inflammatory score | ||||||||||||||
All | −0.96 (0.99) | 0.333 | −1.28 (1.01) | 0.208 | −1.27 (1.02) | 0.215 | −1.35(1.05) | 0.201 | −1.72(1.09) | 0.118 | −2.88(1.32) | 0.032 | −0.06(1.43) | 0.970 |
EPIC-Italy | −1.12 (1.43) | 0.436 | −2.03 (1.47) | 0.170 | −1.45 (1.45) | 0.318 | −1.33(1.57) | 0.400 | −2.36(1.63) | 0.151 | −3.52(1.81) | 0.057 | 1.03(2.67) | 0.701 |
NSHDS | −0.64 (1.37) | 0.640 | −0.25 (1.54) | 0.871 | −0.86 (1.47) | 0.558 | −1.72(1.57) | 0.278 | −1.75 (1.88) | 0.356 | −3.58 (2.70) | 0.196 | −2.56 (1.88) | 0.181 |
(B) Principal component 1 | ||||||||||||||
All | −0.56 (0.53) | 0.297 | −0.74 (0.54) | 0.175 | −0.64 (0.55) | 0.241 | −0.87(0.55) | 0.166 | −1.00(0.57) | 0.083 | −1.55(0.70) | 0.029 | −0.09(0.75) | 0.906 |
EPIC-Italy | −0.75 (0.77) | 0.335 | −1.25 (0.81) | 0.123 | −0.87 (0.79) | 0.273 | −0.83(0.84) | 0.322 | −1.30(0.88) | 0.147 | −1.90(1.04) | 0.074 | 0.83(1.42) | 0.564 |
NSHDS | −0.17 (0.71) | 0.810 | −0.004(0.77) | 0.996 | −0.23 (0.76) | 0.760 | −0.93 (0.81) | 0.253 | −0.85 (0.92) | 0.361 | −1.45 (1.22) | 0.242 | −1.29 (1.02) | 0.214 |
