Table 1 Clinical characteristics and disease severities of patients with major burns on invasive ventilator supporta.

From: Predictors of Early Onset Multiple Organ Dysfunction in Major Burn Patients with Ventilator Support: Experience from A Mass Casualty Explosion

 

Overall, n = 88

Early MODS

P value

No, n = 43

Yes, n = 45

Age

21.3 (4.1)

21.4 (4.8)

21.2 (3.5)

0.825

Male gender

42 (44.7%)

18 (41.9%)

24 (53.3%)

0.281

Mean 2~3TBSA%

60.9 (15.8)

54.2 (15.2)

67.2 (13.7)

<0.001

Facial burn

64 (72.7%)

27 (62.8%)

37 (82.2%)

0.041

≥2nd Smoke inhalation (n = 67)b

17 (23.9%)

9 (26.5%)

8 (21.6%)

0.632

Serum albumin (g/dL)

1.93 (0.69)

2.19 (0.82)

1.71 (0.44)

0.002

Organ failure

  Respiratory

43(48.9%)

12 (27.9%)

31 (68.9%)

<0.001

  Cardiovascular

31 (35.2%)

7 (16.3%)

24 (53.3%)

<0.001

  Hepatic

13 (14.8%)

2 (4.7%)

11 (24.5%)

0.009

  Hematologic

59 (67.0%)

17 (39.5%)

42 (93.3%)

<0.001

  Renal

8 (9.1%)

1 (2.3%)

7 (15.6%)

0.059

  Metabolic

28 (31.8%)

6 (14.0%)

22 (48.9%)

<0.001

  Coagulation

12 (13.6%)

3 (7.0%)

9 (20.0%)

0.075

  No. of organ failure

2.25 (1.44)

1.12 (1.10)

3.33 (1.09)

<0.001

SOFA score

  Day 1

0.78 (1.09)

0.47 (0.77)

1.09 (1.26)

0.006

  Day 3

2.91 (2.18)

1.93 (1.45)

3.84 (2.35)

<0.001

  Day 7

4.95 (3.11)

3.28 (2.57)

6.56 (2.74)

<0.001

  Day 14

4.15 (3.08)

2.81 (2.41)

5.42 (3.12)

<0.001

  Day 21

2.84 (2.70)

1.98 (2.30)

3.67 (2.81)

0.003

Sputum culture

  GNB

34 (38.6%)

12 (27.9%)

22 (48.9%)

0.043

  GPC

3 (3.4%)

2 (4.7%)

1(2.2%)

0.612

  Fungus

5 (5.7%)

4 (9.3%)

1 (2.2%)

0.198

  Bacteremia

21 (23.9%)

9 (20.9%)

12 (26.7%)

0.528

  ECMO

5 (5.7%)

0

5 (11.1%)

0.056

Dialysis

  CVVH

6 (6.8%)

1 (2.3%)

5 (11.1%)

0.246

  HD

1 (1.1%)

0

1 (2.2%)

1.000

  1. aThe data are presented as n (%) unless otherwise stated.
  2. bFiberbronchoscopy is optionally performed if clinically indicated.
  3. TBSA, total body surface area; SOFA, Sequential Organ Failure Assessment; GNB, Gram-negative bacilli; GPC, Gram-positive cocci; ECMO, extracorporeal membrane oxygenation; CVVH, continuous venousvenous hemofiltration; HD, hemodialysis.
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