Table 3 Clinicopathological difference between single- and dual-organ involvement in 204 patients with distal bile duct cancer.
Parameters | N = 204 | Adjacent organ invasion | p-value (χ2 test) | |
|---|---|---|---|---|
single (n = 152), % | dual (n = 52), % | |||
Age | ||||
   <65 y | 113 | 83 (54.6) | 30 (57.7) | 0.699 |
   ≥65 y | 91 | 69 (45.4) | 22 (42.3) |  |
Sex | ||||
   Male | 128 | 93 (61.2) | 35 (67.3) | 0.43 |
   Female | 76 | 59 (38.8) | 17 (32.7) |  |
Gross type | ||||
   Papillary | 7 | 7 (4.6) | 0 (0) | 0.039 * |
   Nodular | 21 | 18 (11.8) | 3 (5.8) |  |
   Infiltrative | 176 | 127 (83.6) | 49 (94.2) |  |
Histological grade | ||||
   Well | 33 | 27 (17.8) | 6 (11.5) | 0.565* |
   Moderate | 127 | 92 (60.5) | 35 (67.3) |  |
   Poor | 44 | 33 (21.7) | 11 (21.2) |  |
N criteria | ||||
   0 | 100 | 83 (54.6) | 17 (32.7) | 0.022 * |
   1 | 84 | 55 (36.2) | 29 (55.8) |  |
   2 | 20 | 14 (9.2) | 6 (11.5) |  |
Size (cm) | ||||
   <2.5 | 92 | 70 (46.1) | 22 (42.3) | 0.639 |
   ≥2.5 | 112 | 82 (53.9) | 30 (57.7) |  |
Lymphatic invasion | ||||
   Not identified | 107 | 85 (55.9) | 22 (42.3) | 0.09 |
   Present | 97 | 67 (44.1) | 30 (57.7) |  |
Perineural invasion | ||||
   Not identified | 53 | 39 (25.1) | 14 (26.9) | 0.857 |
   Present | 151 | 113 (74.3) | 38 (73.1) |  |
Margin involvement | ||||
   Not involved | 178 | 129 (84.9) | 49 (94.2) | 0.081 |
   Involved | 26 | 23 (15.1) | 3 (5.8) |  |
