Table 6 Haplotype distribution in extreme BMD groups, and in the two halves of the complete BARCOS cohort according to LS-BMD mean (upper half > 0.8509; lower half < 0.8509).

From: Common and rare variants of WNT16, DKK1 and SOST and their relationship with bone mineral density

Haplotype

Extreme BMD

Complete BARCOS cohort

HBM (n = 110)

LBM (n = 106)

Upper half (n = 1159)

Lower half (n = 1295)

DGDAC

60

67

653

748

IAIGT

30

21

345

310

DADAT

18

16

183

220

DAIGT

0

1

20

29

p-valuea

0.351

0.012

p-valueb

0.1865

0.0022

  1. ap-value for the 2 × 4 contingency table.
  2. bp-value for the 2 × 2 contingency table including only the 2 associated haplotypes.
  3. Nominal significant values are in italic, Bonferroni’s significant values are in bold.
Back to article page