Figure 3
From: Beyond autophagy: a novel role for autism-linked Wdfy3 in brain mitophagy
Perinatal mortality and survival of Wdfy3 insufficient pups. (A) Average number of pups born or weaned per litter (data collected from 11 WT and 6 Wdfy3lacZ female breeders, respectively, for each of the breeder schemes) born to either Wdfy3lacZ male x WT female or Wdfy3lacZ female x WT male. Later, these pups were utilized for behavioral and biochemical tests. Statistics was performed by Mann-Whitney test. (B) Number of live litters on postpartum day 21 (post-weaning) relative to the number of live litters born. Both sets of data were compared to the published value of 0.92 for the C57BL/6J strain. The significant p value was obtained by using the test for one proportion (Z-statistic = 2.284; 95%CI 47.64 to 93.67). (C) The average number of female or male pups per year (from 2013 until July 2017) and by genotype. Statistics was performed by Kruskal-Wallis test, followed by Dunn’s multiple comparisons post-hoc test. Data for panels (A,C) were visualized utilizing box-and-whiskers plots in which the top and bottom lines represent the highest and lowest values whereas the height of the box, represents the interquartile range. The line in the middle of the box represents the median.
