Figure 5
Hz-containing compartments likely originate from the DV. 3D7 parasites were loaded with 5 µM Fluo-4 AM for 1 h, then washed and left untreated (A), or incubated with 20x IC50 CQ for 2 h (B). Fluo-4 remained trapped in the DV of control parasites for the duration of the experiment. CQ-treated parasites showed co-localization of the DV-derived Fluo-4 staining (white arrows) with cytoplasmic hemozoin (black arrows). Scale bars, 5 µm.
