Figure 6

(a) Circos plot of the overlapping cis and trans-eQTLs on chromosome 5 (rs4958465) and 10 (rs117677211). Blue lines in the centre connect rs4958465 to genes with effects in trans and orange lines connect rs117677211 to genes that it effects in trans. (b) rs117677211-ITGB1 cis-eQTL on chromosome 10 and the genes that it effects in trans. (c) rs4958465-SPARC cis-eQTL on chromosome 5 and the genes that it effects in trans. (d) Heatmap of tissue specific expression of rs4958465 cis and trans genes, female reproductive tissues outlined in black.