Figure 1
From: The polymorphism rs35767 at IGF1 locus is associated with serum urate levels
Effect of IGF-1 on urate excretory transporters, mRNA and protein levels. HEK293 cells were incubated in presence of increasing IGF-1 concentrations (5, 10, 50 nM). mRNA levels were measured by Real Time RT-PCR. (a) MRP4 mRNA levels; (b) MRP4 protein levels; (c) NTP1 mRNA levels; (d) NPT1 protein levels; (e) BCRP mRNA levels; (f) BCRP protein levels. Data are means ± SD of three independent experiments, each done in triplicate. *P < 0.02 and **P < 0.01 vs. basal. To see the original blots from which these images were taken, please refer to the Online Supplementary Information (Supplemental Fig. 1).
