Figure 3

Identification of candidate response markers using ultra-high resolution FT-ICR MS/MS. Spots that show highest feature of interest intensity were re-measured and fragmented using a SolariX 7 T XR FTICR mass spectrometer with R = 500,000. For this reason a spot containing cells treated with 1 µM Imatinib was used for re-measurement and fragmentation of the feature m/z 616.1766 (a) and a spot containing DMSO-treated cells was used for fragmentation of the feature m/z 826.5722 (b).