Table 4 Age-standardised incidence rates (aSIRs), hazard ratios (HRs) and 95 percent confidence intervals (95% CIs) of fatal myocardial infarction (MI) by oral health status between 1973 and 2012.

	Cases of MI (N)	Person-years	aSIR (per 100,000 person-years)^*	Minimally-adjusted HR^† (95% CI)	Fully-adjusted HR^‡ (95% CI)
Number of teeth§
6	122	310,713	95.3	1.00	1.00
4–5	191	105,356	155.5	—	—
age <80 years^\|\|	110	60,559	225.0	1.58 (1.16–2.14)	1.51 (1.11–2.05)
age ≥80 years^\|\|	81	44,796	69.8	1.31 (0.88–1.96)	1.28 (0.85–1.92)
2–3	184	51,847	215.6	—	—
age <80 years^\|\|	105	21,305	497.2	2.21 (1.60–3.05)	2.06 (1.49–2.84)
age ≥80 years^\|\|	79	30,542	77.7	1.32 (0.87–2.00)	1.25 (0.82–1.90)
0–1	440	80,294	265.9	—	—
age <80 years^\|\|	223	26,434	597.3	2.75 (2.03–3.74)	2.48 (1.82–3.37)
age ≥80 years^\|\|	217	53,861	86.3	1.30 (0.88–1.93)	1.29 (0.87–1.91)
P-trend (age <80)				<0.001	<0.001
P-trend (age ≥80)				0.38	0.40
Dental plaque
No plaque	78	100,536	101.1	1.00	1.00
Low	265	298,161	126.0	1.10 (0.85–1.42)	1.07 (0.83–1.39)
High	154	69,219	244.0	1.66 (1.25–2.21)	1.56 (1.16–2.09)
Not accurate^#	440	80,294	265.9	—	—
Oral lesions
No lesions^**	466	399,745	149.8	1.00	1.00
Candida-related	99	24,487	248.0	1.30 (1.03–1.63)	1.24 (0.99–1.57)
Denture-related	366	85,835	235.5	—	—
age <80 years^\|\|	192	35,385	519.9	1.46 (1.20–1.78)	1.37 (1.12–1.68)
age ≥80 years^\|\|	174	50,450	82.2	1.02 (0.82–1.26)	1.01 (0.81–1.26)
Tongue	204	74,578	212.0	1.20 (1.02–1.43)	1.20 (1.02–1.43)

^*Age-standardised incidence rate per 100,000 person-years, standardised to the age distribution of person-years experienced by all participants, using 5-year age categories. ^†Minimally-adjusted HRs: All Cox proportional hazards regression models had attained age as the time scale, stratified by sex (male, female) and attained calendar period in 5-year intervals. ^‡Fully-adjusted HRs: Cox proportional hazards regression models had attained age as time scale, adjusted for alcohol consumption (no/low, moderate/high) and area of residence (small town, rural, city), and stratified by sex, smoking and snus use (uses neither, smoker only, snus user only, uses both) and attained calendar period in 5-year intervals. ^§Number of teeth was assessed at baseline through examination of six reference teeth (tooth numbers 16, 21, 24, 36, 41, 44 using the Ramfjord teeth index). ^||Refers to attained age. Model contained an interaction term between the oral health exposure and attained age (<80 years, ≥80 years). ^#The measurement of dental plaque for individuals with only 0 or 1 of the reference teeth present was considered to not be accurate (n = 4,624). ^**Reference group included those without any evidence of Candida-related, denture-related, or tongue lesions.

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