Table 1 LDA Followed by Cross-Validation for Classification of ELD, MONO and HC groups.

From: Identification of Urine Metabolites as Biomarkers of Early Lyme Disease

LC-MS Analysis

Sample Group^

No. Pos. (% Pos.)

LDA: Leave-One-Out#

LDA: Leave-Two-Out*

ELD versus HC

ELD versus MONO

ELD versus HC

ELD versus MONO

Positive Ion Mode

HC

12 (86)

323 (85)

ELD

12 (86)

12 (86)

324 (86)

327 (87)

MONO

14 (100)

376 (99)

Negative Ion Mode

HC

12 (86)

320 (85)

ELD

10 (71)

13 (93)

252 (67)

351 (93)

MONO

13 (93)

354 (94)

  1. Abbreviations: LDA, linear discriminant analysis; LC-MS, liquid chromatography mass spectrometry; No., number; Pos., positive; ELD, early Lyme disease; HC, healthy controls; MONO, infectious mononucleosis. ^A total of 14 samples were analyzed for each group. #A total of 14 possible results exist for a leave-one-out analysis using 14 samples per group. *A total of 378 possible results exist for a leave-two-out analysis using 14 samples per group.