Figure 2

Maternal plasma concentrations of (a) ANGPTL4 and (b) linoleic acid (LA, 18:2 n-6) at 15, 24 and 32 weeks of pregnancy, in pregnant women with overweight and obesity classified by GWG conformed to the recommended rate of weight gain during such interval of pregnancy made by the IOM for their particular pre-pregnancy BMI: between 3.4 and 5.5 kg for women with overweight and between 3 and 4.6 kg for women with obesity. Open bars, data pregnant women with GWG < IOM recommendation; filled grey bars, data from pregnant women with GWG within IOM recommendation; filled black bars, data from pregnant women with GWG > IOM recommendation. For each subgroup, different superscripted upper-case letters indicate significant differences (P < 0.001) between different weeks of pregnancy, whereas different superscripted lower-case letters indicate significant differences (P < 0.001) between subgroups at each stage of gestation analyzed (i.e. 15, 24 and 32 weeks of pregnancy). Maternal parameters were adjusted by pre-pregnancy BMI. All values are mean ± SEM. ⁽¹⁾log-transformed for statistical comparisons.