Figure 6
Effect of downregulated HOTAIR on tumorgenesis in vivo. (A) Tumors from nude mice after injection of QBC939 cells transfected with shHOTAIR or shCtrl. (B) Tumor volume was measured every 3 days after injection; (C) After 18 days of injection, the nude mice and tumor weights. (D) The Ki67 expression and positive cell numbers was determined by immunohistochemical staining. (E) qRT-PCR was performed to detect the average expression of HOTAIR. *P < 0.05, **P < 0.01.
