Figure 5

Serum levels of 25(OH)D3 in mice treated with and without UV radiation. The shaved dorsal surfaces of female C57Bl/6 mice on vitamin D deficient diets (D−) were irradiated with 1 kJ/m2 ultraviolet radiation daily for 4 days before undergoing DSS treatment. (A) 25(OH)D3 levels 24 h after four doses of UVB irradiation. (B) 25(OH)D levels after 6 days of DSS treatment in a separate group of mice. Solid bars control mice, open bars DSS mice. Values are expressed as mean ± SEM, from two experiments. n = 4/group day 0 and n = 7–8/group day 7. **P < 0.01, ***P < 0.001.