Figure 3
Effects of CyP on microRNA, IRAK1 and TRAF6 expressions. Time-dependent experiments of human monocytes incubated with CyP at the final concentration of 10 µg/ml and analysis of miR-146a (A) and miR-155 expression (B). Experiments with cells incubated with E. coli LPS (1 µg/ml) were performed as controls. The results are expressed as mean ± S.D. of triplicate data. Effects of CyP on miR-146a (C), miR-155 (D), IRAK1 (E) and TRAF6 (F) expressions in experiments of cross-tolerance with E. coli LPS. Data are presented as mean ± S.D. of triplicate data of one representative experiment of two performed. *p < 0,05; ***p < 0,001 (ANOVA with Tukey’s multiple comparison post hoc test).
