Figure 1 | Scientific Reports

Figure 1

From: Gomesin inhibits melanoma growth by manipulating key signaling cascades that control cell death and proliferation

Figure 1

(a) Schematic of 84-residue precursor encoding the gomesin homolog HiGom. The signal peptide, mature gomesin, and propeptide are shown in magenta, black and green, respectively. Note that Z = pyroglutamate. (b) Sequence alignment showing amino acid identities (boxed in black) between HiGom and AgGom. Disulfide bond connectivities are shown above the alignment. (c) Schematic of the AgGom structure showing the disulfide-stabilized β-hairpin (PDB file 1KFP).

Back to article page