Table 1 Antimicrobial activity of gomesin peptides from A. gomesiana (AgGom) and H. infensa (HiGom) against a range of Gram-positive and Gram-negative bacteria.
MIC (μM) | MBC (μM) | |||
|---|---|---|---|---|
AgGom | HiGom | AgGom | HiGom | |
Gram-positive bacteria | ||||
Staphylococcus aureus ATCC 25923 | >28 | 28 | >28 | 28 |
Enterococcus faecalis ATCC 51299 VanB | 28 | 14 | 28 | 14 |
Enterococcus faecalis Van A | 7 | 3.5 | 7 | 7 |
Bacillus subtilis ATCC 6633 | 0.875 | 0.656 | 0.875 | 0.875 |
Bacillus megaterium ATCC 13632 | ≤0.014 | ≤0.014 | ≤0.014 | ≤0.014 |
Streptococcus pneumoniae ATCC 33400 | >28 | >28 | >28 | >28 |
Staphylococcus aureus ATCC 43300 MRSA | >28 | >28 | >28 | >28 |
Staphylococcus aureus ATCC 29213 MRSA | >28 | >28 | >28 | >28 |
Staphylococcus epidermidis GISA | 14 | 7 | 14 | 7 |
Gram-negative bacteria | ||||
Escherichia coli ATCC 25922 | 14 | 14 | 14 | 14 |
Klebsiella pneumonia ATCC 700603 | >28 | 28 | >28 | 28 |
Klebsiella pneumoniae ATCC 13883 | 14 | 7 | 14 | 7 |
Pseudomonas aeruginosa ATCC 10145 | >28 | >28 | >28 | >28 |