Figure 2

GRK2 knockdown alters glomerular maturation and count. (a) Representative images of Periodic-Acid Schiff stained histological kidney sections and mean ± S.E.M of the number of mature glomeruli in low power field (LPF) from postnatal day 7 (P7) shGRK2 and age-matched C57Bl/6 mice. Scale bar is 20 µm (n = 6). (b) Representative images of H&E stained histological kidney sections and mean ± S.E.M of the number of mature glomeruli/mm2 from 6-month-old shGRK2 and age-matched C57Bl/6 mice. Scale bar is 100 µm (n = 6). * denotes significantly different at (p < 0.05, unpaired Student’s t test).