Table 1 Biochemical analysis of urine from shGRK2 mice.

From: GRK2 knockdown in mice exacerbates kidney injury and alters renal mechanisms of blood pressure regulation

Analyte (unit)

1-month old (n = 6)

3-month-old (n = 6)

6-month-old (n = 6)

C57Bl/6

shGRK2

C57Bl/6

shGRK2

C57Bl/6

shGRK2

Sodium (mmol/L)

199 ± 46

149 ± 44*

160 ± 61

112 ± 23*

175 ± 30

105 ± 53*

Potassium (mmol/L)

72 ± 23

87 ± 4

91 ± 6

104 ± 14

94 ± 6

83 ± 14

Chloride (mmol/L)

198 ± 60

232 ± 61

232 ± 43

245 ± 56

233 ± 31

165 ± 66

Calcium (mg/dL)

5.2 ± 1.2

4.9 ± 1.3

5.2 ± 1.3

6.6 ± 1.4

5.1 ± 0.2

5.9 ± 0.01

Albumin (g/L)

0.15 ± 0.1

0.1 ± 0.01

0.7 ± 0

0.5 ± 0.34

0.6 ± 0.1

0.7 ± 0.05

Creatinine (mg/dL)

25 ± 12

26 ± 5

37 ± 4

30 ± 16

38 ± 2

40 ± 1

  1. Biochemical analysis of urine collected from 1-, 3- and 6-month-old shGRK2 and age-matched C57Bl/6 mice (n = 6). * denotes significantly different at (p < 0.05, unpaired Student’s t test).
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