Figure 3
From: RDM1 plays an oncogenic role in human lung adenocarcinoma cells
Knockdown of RDM1 inhibits human lung adenocarcinoma cell growth in vivo. (A) Total protein was isolated from stable RDM1- knockdown (shRDM1) cell line and analyzed by immunoblotting with the antibodies against RDM1. (B) A549 cells with the stable RDM1- knockdown (shRDM1) were injected subcutaneously into 6-week old immunocompromised mice. At endpoint, tumors were removed, photographed and measured. (C) The weights of tumors are presented as Mean ± S.D. (n = 5) *p < 0.05. (D) IHC staining of RDM1 was performed for RDM1-knockdown (shRDM1) or control (shN) tumors.
