Figure 1 | Scientific Reports

Figure 1

From: Expression and localization of the polarity protein CRB2 in adult mouse brain: a comparison with the CRB1rd8 mutant mouse model

Figure 1

CRB2 localization in mouse brain. (A) Immunofluorescence of CRB2 in a sagittal section of the adult WT brain showing a punctate CRB2 labeling throughout the section, being more evident in certain nuclei of specific areas: Cortex (Cx), Hippocampus (Hc), cerebellum (Cb), Mesencephalic Trigeminal Nucleus (Me5), optic tract (opt) and Hypothalamus (H) (yellow arrowheads). (B) Immunohistochemistry of CRB2 in a coronal section of the hypothalamus. CRB2 labeling is especially evident in certain nuclei like the Dorsal area (DA), Periventricular Nucleus (PVN), Dorsomedial Hypothalamic Nucleus (DMH), Ventromedial Hypothalamic Nucleus (VMH), Lateral Retrochiasmatic area (RchL), Lateral Hypothalamic Arcuate Nucleus (ArcL), Retrochiasmatic Supraoptic Nucleus (SOR). (C) Immunofluorescence of CRB2 in a coronal adult mouse of the hypothalamic area showing a highly organized punctate labeling for CRB2 arranged from the DA to the SOR regions (yellow arrowheads). DAPI (in blue): nuclear labeling. Scale bars: 200 µm (A–C).

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