Figure 1
From: Hydrodynamic trapping measures the interaction between membrane-associated molecules
Schematic illustration of the experiments and the studied molecules. (A–C) Hydrodynamic trapping of membrane-anchored molecules in an SLB is achieved by applying negative pressure through a micropipette (tip radius ~ 1 μm). This results in accumulation of the molecules in the SLB. Not drawn to scale. (D) The accumulation depends on the applied pressure and the distance between the pipette and the SLB. (E) Dimensions of the studied molecules: human CD45 (CD45d1-d4: PDB 5FMV + mucin-like region), human CD4 (PDB 3T0E), rat CD2 (PDB 1HNG) and SA (PDB 3RY2).
