Table 3 Descriptive statistics (mean ± standard deviation) of calculated parameters in the ACLT (N = 12) and Control (N = 16) groups, and the statistical differences within them.

From: Iterative and discrete reconstruction in the evaluation of the rabbit model of osteoarthritis

Parameter

ACLT

Control

p -values

ACLT

Control

p -values

ACLT

Control

p -values

1/2 of full data

CGLS

TV

DART

Subchondral bone plate

Pl.Th

(%)

531.5 ± 92.6

483.3 ± 99.6

0.254 (0.508)

533.2 ± 93.3

486.2 ± 97.9

0.254 (0.508)

527.6 ± 90.9

484.6 ± 99.4

0.316 (0.631)

Trabecular bone

BV/TV

(%)

47.9 ± 4.3**

51.7 ± 3.4

0.019 (0.037)

49.8 ± 4.3*

53.2 ± 3.2

0.026 (0.053)

47.6 ± 4.8**

51.9 ± 3.7

0.015 (0.029)

Tb.Th

(µm)

202.8 ± 16.4

213.7 ± 16.4

0.061 (0.121)

220.5 ± 16.8

228.4 ± 17.2

0.140 (0.280)

199.2 ± 18.5*

213.1 ± 17.6

0.033 (0.066)

Tb.S

(µm)

308.2 ± 45.8

283.8 ± 25.7

0.111 (0.223)

311.7 ± 45.2

287.9 ± 24.0

0.087 (0.174)

305.8 ± 41.5

281.7 ± 25.9

0.095 (0.189)

Tb.N

(mm−1)

2.37 ± 0.18

2.42 ± 0.12

0.265 (0.529)

2.26 ± 0.17

2.34 ± 0.12

0.148 (0.296)

2.40 ± 0.18

2.44 ± 0.11

0.353 (0.706)

EF

(a.u.)

−0.201 ± 0.06**

−0.268 ± 0.05

0.002 (0.004)

−0.203 ± 0.05**

−0.277 ± 0.05

0.002 (0.004)

−0.189 ± 0.05**

−0.263 ± 0.05

0.001 (0.002)

1/4 of full data

CGLS

TV

DART

Subchondral bone plate

Pl.Th

(%)

540.2 ± 93.6

490.2 ± 98.1

0.211 (0.423)

543.3 ± 93.9

495.2 ± 96.5

0.186 (0.371)

524.6 ± 94.8

486.86 ± 97.9

0.332 (0.664)

Trabecular bone

BV/TV

(%)

52.0 ± 4.3**

55.4 ± 3.3

0.024 (0.047)

53.8 ± 4.8

57.1 ± 3.5

0.055 (0.110)

47.4 ± 4.2**

52.6 ± 4.2

0.002 (0.004)

Tb.Th

(µm)

236.7 ± 16.0

243.1 ± 17.4

0.186 (0.371)

255.4 ± 19.9

260.2 ± 18.5

0.316 (0.631)

202.8 ± 18.3**

219.3 ± 17.9

0.021 (0.042)

Tb.S

(µm)

306.4 ± 45.9

281.6 ± 24.6

0.073 (0.146)

314.9 ± 46.0

289.1 ± 25.2

0.103 (0.205)

304.5 ± 46.1

276.4 ± 27.4

0.061 (0.121)

Tb.N

(mm−1)

2.20 ± 0.14

2.28 ± 0.11

0.080 (0.159)

2.11 ± 0.14*

2.20 ± 0.12

0.045 (0.090)

2.34 ± 0.19

2.40 ± 0.11

0.198 (0.397)

EF

(a.u.)

−0.205 ± 0.04**

−0.280 ± 0.04

0.001 (0.002)

−0.190 ± 0.05**

−0.280 ± 0.04

0.001 (0.002)

−0.187 ± 0.04**

−0.253 ± 0.04

0.001 (0.002)

1/6 of full data

CGLS

TV

DART

Subchondral bone plate

Pl.Th

(%)

548.4 ± 96.3

498.3 ± 93.7

0.130 (0.260)

551.9 ± 96.8

501.4 ± 92.9

0.130 (0.260)

524.2 ± 95.7

488.9 ± 97.1

0.349 (0.698)

Trabecular bone

BV/TV

(%)

54.4 ± 5.8

58.5 ± 5.0

0.055 (0.110)

55.6 ± 6.4

59.9 ± 5.5

0.061 (0.121)

47.5 ± 4.0**

52.6 ± 4.2

0.002 (0.004)

Tb.Th

(µm)

270.3 ± 24.4

276.5 ± 47.1

0.332 (0.664)

285.6 ± 28.2

291.5 ± 27.5

0.437 (0.873)

202.1 ± 15.4**

219.2 ± 18.3

0.010 (0.020)

Tb.S

(µm)

321.0 ± 47.1

294.1 ± 27.9

0.130 (0.260)

328.1 ± 48.4

299.8 ± 29.9

0.120 (0.241)

301.8 ± 43.6

277.9 ± 28.2

0.095 (0.189)

Tb.N

(mm−1)

2.02 ± 0.15*

2.12 ± 0.13

0.041 (0.082)

1.95 ± 0.15**

2.05 ± 0.12

0.021 (0.042)

2.35 ± 0.18

2.40 ± 0.12

0.268 (0.537)

EF

(a.u.)

−0.179 ± 0.04**

−0.234 ± 0.05

0.001 (0.002)

0.180 ± 0.05**

−0.252 ± 0.04

0.001 (0.002)

−0.182 ± 0.04**

−0.240 ± 0.05

0.002 (0.004)

  1. Used algorithm and fraction of full projection data used to reconstruct different datasets denoted in the headers. Statistical difference was tested with non-parametric Mann-Whitney testing (exact), p-values listed as one-tailed (two-tailed). *Values significantly different from the Control group (one-tailed p < 0.05). **Values significantly different from the Control group (two-tailed p < 0.05).