Figure 5 | Scientific Reports

Figure 5

From: Gold nanoparticles-induced cytotoxicity in triple negative breast cancer involves different epigenetic alterations depending upon the surface charge

Figure 5

Electron micrographs showing the distribution and internalisation of AuNPs in MDA-MB-231 cells. 5a (A) & 5b (A) show TEM images of untreated MDA-MB-231 cells 5a (B) and 5b (B) Formation of pseudopodia by MDA-MB-231 cells with AuNPs in centre; 5a (C) & 5b (C,D) Localisation of AuNPs inside the vesicles; 5a (D) & 5b (E) Internalisation of AuNPs; 5a (E) and 5b (H,I) HRTEM images of untreated MDA-MB-231 cells; 5a (F–H) HRTEM images of MDA-MB-231 cells treated with 100 μg/mL, 250 μg/mL and 500 μg/mL of citrate-capped AuNPs respectively; 5b (F,G) TEM images of cysteamine-capped AuNPs treated cells; 5b (J) HRTEM image showing localisation of cysteamine-capped AuNPs inside the mitochondria; 5b (K,L) HRTEM image of MDA-MB-231 cells treated with cysteamine-capped AuNPs. Red arrows in the images are pointing towards AuNPs.

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