Table 3 Bovine corneal opacity and permeability. Opacity and permeability values of bovine corneas as per the OECD BCOP 437 guidelines.
Sl no | Exposure | Opacity | Permeability | IVIS | UN GHS |
|---|---|---|---|---|---|
1 | Negative control* | 3 ± 0.28 | 0.00 | 3 ± 0.28 | No category |
2 | 5 mg/ml | 18.28 ± 0.12 | 0.024 ± 0.22 | 18.64 ± 0.19 | No prediction can be made |
3 | 25 mg/ml | 19.01 ± 0.09 | 0.010 ± 0.41 | 19.37 ± 0.25 | No prediction can be made |
4 | 50 mg/ml | 19.85 ± 0.31 | 0.008 ± 0.19 | 19.97 ± 0.46 | No prediction can be made |
5 | Positive control* | 50.22 ± 0.16 | 1.120 ± 0.34 | 67.02 ± 0.45 | Category 1 |