Table 3 Bovine corneal opacity and permeability. Opacity and permeability values of bovine corneas as per the OECD BCOP 437 guidelines.

From: Fundamental pharmacological expressions on ocular exposure to capsaicin, the principal constituent in pepper sprays

Sl no

Exposure

Opacity

Permeability

IVIS

UN GHS

1

Negative control*

3 ± 0.28

0.00

3 ± 0.28

No category

2

5 mg/ml

18.28 ± 0.12

0.024 ± 0.22

18.64 ± 0.19

No prediction can be made

3

25 mg/ml

19.01 ± 0.09

0.010 ± 0.41

19.37 ± 0.25

No prediction can be made

4

50 mg/ml

19.85 ± 0.31

0.008 ± 0.19

19.97 ± 0.46

No prediction can be made

5

Positive control*

50.22 ± 0.16

1.120 ± 0.34

67.02 ± 0.45

Category 1

  1. *Negative control = Phosphate Buffer 7.4.
  2. *Positive control = Benzalkonium chloride, 5%.