Figure 3

Theoretical prediction of synaptic modification based on the initial synaptic strengths in the presence of a frequency mismatch. In the presence of a frequency mismatch Δν, the instantaneous fixed point of the time lag is numerically calculated by self-consistently solving Eq. (8) with the Newton-Raphson root-finding method. (A–C) Frequency mismatch Δν = 0.02 Hz with ν2 > ν1. (D–F) Frequency mismatch Δν = 0.04 Hz with ν2 > ν1. In the presence of frequency mismatch the output synapse of the neuron with higher frequency is more likely to be potentiated, while the reverse synapse is depressed.