Figure 7

Illustration of the accordance between two-neuron theoretical framework and network simulation results. (A–D) The probability P_asym as a measure of asymmetry in the two-neuron motif (solid) and the asymmetry index \({C}_{{\rm{net}}}\) for the neuronal network (dotted curves) are calculated in the presence of different axonal propagation delays with τ_a = 0.3 ms (red) and τ_a = 1.0 ms (blue curves). (A) The effect of the firing frequency on P_asym (C_net) in the two-neuron motif (network simulation) with inhomogeneity in the initial distribution of the synaptic strengths represented by σ_g. In the figure σ_g = 0.05. (B) Same as A, but in the presence of inhomogeneity in the firing frequencies indicated by Δν (\({\sigma }_{\nu }\)) in the two-neuron motif (network simulation). In the figure Δν = σ_ν = 0.01 Hz. (C) The effect of inhomogeneity in the frequencies Δν (σ_ν) on P_asym (C_net). In the figure ν = 80 Hz and σ_g = 0.05. (D) Same as C, but for inhomogeneity in the initial distribution of the synaptic strengths σ_g. In the figure ν = 80 Hz and Δν = σ_ν = 0.01 Hz. (a₁–d₁) Samples of final coupling matrix indexed by the number of pre- (j) and postsynaptic (i) neurons correspond to a₁–d₁ markers in A–D, representing the value of the asymmetry index C_net = 0.31,0.00,0.75,0.64,0.62,0.80 in the simulated network, respectively.