Figure 3 | Scientific Reports

Figure 3

From: Targeting proinflammatory cytokines ameliorates calcifying phenotype conversion of vascular progenitors under uremic conditions in vitro

Figure 3

Dose-dependent induction of osteoblastic differentiation in MSC by URS. (A) ALP activity in MSC treated with different concentrations of toxins in OM for 7 days. (B) Calcium deposited by MSC cultured for 3 weeks in OM with increasing URS concentrations. “Fold cmax” denotes the x-fold concentration of the highest concentration. Values were normalized to protein content and are expressed relative to OM without URS (set 1.00). Means + SEM, n = 4–6. *P < 0.05, **P < 0.01, ***P < 0.001.

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