Figure 5
Liver damage triggers increase of GRP78 serum concentration. (A,B) WT mice were infected with 2 × 106 PFU of LCMV WE strain without BDL and (A) ALT, AST levels were determined in the infected mice at day 8, 10 and 12 post infection (n = 8). (B) GRP78 was measured in the serum (n = 3–9) (C–E) Human GRP78 levels in patient serum is represented as a function of (C) ALT, (D) AST and (E) bilirubin from the patient cohort described in Supplementary Table 3 (n = 77).
