Figure 1 | Scientific Reports

Figure 1

From: Aristolochic acid I determine the phenotype and activation of macrophages in acute and chronic kidney disease

Figure 1

Induction of acute kidney injury. (A) Kidney weight, creatinine, and BUN; kidney injury score and infiltration of inflammatory cells, wildtype mice underwent surgery or intervention and kidneys were harvested 3 days later. Renal sections were stained with PAS (B), neutrophils (C) and F4/80 (D) Images illustrate representative sections. The indices for cell infiltration or fibrosis were determined by quantitative morphometry as described in the methods section. Values represent means ± SEM from 30 high power fields of investigated kidneys from 6–10 mice in each group. Data are expressed as means ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001 versus control animal group of the same time point.

Back to article page