Figure 4 | Scientific Reports

Figure 4

From: Astrocyte-specific overexpression of Nrf2 protects against optic tract damage and behavioural alterations in a mouse model of cerebral hypoperfusion

Figure 4

Increased microglia/macrophages in response to hypoperfusion. (a) % Area of Iba1+ staining in the corpus callosum and (b) internal capsule was unchanged following cerebral hypoperfusion. (c) % Area of Iba1+ staining in the optic tract was significantly altered by cerebral hypoperfusion (F(1,32) = 14.74, p = 0.001), with no effect of genotype. (d) Representative images of Iba1+ staining in the optic tract. Scale bar 100 µm. Mean ± SEM. Two-way ANOVA with Bonferroni adjustment for post hoc analysis. *p < 0.05, ** p < 0.01. n = 8–10 per group.

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