Table 1 30 genes with annotations most highly up-regulated in quiescent P. vivax sporozoites.

From: Unraveling the Plasmodium vivax sporozoite transcriptional journey from mosquito vector to human host

Gene ID

Product description

Gene symbol

p -value

PVP01_1105500

nucleoside diphosphate kinase, putative

NDK

<0.0001

PVP01_1132600

TRAP-like protein, putative

TLP

<0.0001

PVP01_0613800

merozoite TRAP-like protein, putative

MTRAP

<0.0001

PVP01_1226800

nicotinamide/nicotinic acid mononucleotide adenylyltransferase, putative

NMNAT

0.0093

PVP01_1124400

sphingomyelin synthase 2, putative

SMS2

0.0160

PVP01_0607900

phospholipid scramblase, putative

 

0.0003

PVP01_1258000

gamete egress and sporozoite traversal protein, putative

GEST

0.0143

PVP01_1249700

thioredoxin 1, putative

TRX1

<0.0001

PVP01_0920900

CorA-like Mg2+ transporter protein, putative

MIT1

<0.0001

PVP01_1245400

phosphatidylinositol-4-phosphate 5-kinase, putative

PIP5K

<0.0001

PVP01_0615300

claudin-like apicomplexan microneme protein, putative

CLAMP

<0.0001

PVP01_1224800

apicoplast calcium binding protein 1, putative

ACBP1

<0.0001

PVP01_1436800

thrombospondin-related apical membrane protein, putative

TRAMP

0.0010

PVP01_1321700

CorA-like Mg2+ transporter protein, putative

MIT3

0.0003

PVP01_1212700

iron regulatory protein, putative

IRP

<0.0001

PVP01_0114800

serine/threonine protein kinase, FIKK family

FIKK

<0.0001

PVP01_0943700

alpha/beta hydrolase, putative

alpha/beta hydrolase

<0.0001

PVP01_0928000

tRNA (guanine-N (7)-)-methyltransferase, putative

tRNA (guanine-N (7)-)-methyltransferase

<0.0001

PVP01_0728800

merozoite surface protein 1 paralog

MSP1P

0.0010

PVP01_1223600

protein kinase, putative

PK

<0.0001

PVP01_0313300

calcium-dependent protein kinase 4, putative

CDPK4

0.0014

PVP01_1141700

uroporphyrinogen III decarboxylase, putative

UROD

<0.0001

PVP01_1456100

COPI associated protein, putative

COPI

<0.0001

PVP01_1464100

DNA replication origin binding protein, putative

DIA2

0.0007

PVP01_0112200

plasmepsin X, putative

PMX

<0.0001

PVP01_1322600

phosphoenolpyruvate carboxylase, putative

PEPC

0.0171

PVP01_0303900

6-cysteine protein, putative, pseudogene

6-cys

<0.0001

PVP01_0921000

alpha/beta hydrolase fold domain containing protein, putative

alpha/beta hydrolase

<0.0001

PVP01_0519100

vacuolar protein sorting-associated protein 2, putative

VPS2

0.0002

PVP01_0906300

centrin-4, putative

CEN4

<0.0001

  1. This table represents differentially expressed genes (0 h vs 4 h, 37 °C) with exclusion of unannotated genes.
  2. Refer to Supplemental Data S3 for complete data set.
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