Table 3 30 genes with annotations most highly up-regulated in P. vivax sporozoites transitioning into early liver-stage parasites.

From: Unraveling the Plasmodium vivax sporozoite transcriptional journey from mosquito vector to human host

Gene ID

Product description

Gene symbol

p -value

PVP01_0616100

ookinete surface protein P25

Pvs25

0.0001

PVP01_0929800

parasitophorous vacuolar protein 1, putative

PV1

0.0070

PVP01_1444300

haloacid dehalogenase-like hydrolase, putative

HAD3

0.0063

PVP01_1255700

E3 SUMO-protein ligase NSE2, putative

NSE2

0.0001

PVP01_0905900

histone 2B, putative

H2B

<0.0001

PVP01_1131700

histone H2A, putative

H2A

<0.0001

PVP01_1130100

cell division cycle protein 48 homologue, putative

 

0.0025

PVP01_1330600

calmodulin, putative

 

0.0001

PVP01_1265900

KS1 protein precursor, putative

 

0.0171

PVP01_1267100

triosephosphate isomerase, putative

 

0.0206

PVP01_0816000

enolase, putative

ENO

0.0034

PVP01_0815800

tubulin binding cofactor c, putative

 

0.0310

PVP01_1255200

sortilin, putative

 

0.0080

PVP01_0713100

major facilitator superfamily-related transporter, putative

MFR4

0.0057

PVP01_1238100

eukaryotic initiation factor 4a, putative

eIF4A

0.0002

PVP01_0905800

histone H4, putative

H4

0.0026

PVP01_0507600

receptor for activated c kinase, putative

RACK1

0.0237

PVP01_0808500

nucleolar protein 5, putative

NOP5

0.0066

PVP01_1208500

DNA/RNA-binding protein Alba 2, putative

ALBA2

0.0004

PVP01_1212100

DNA-directed RNA polymerases I, II, and III subunit RPABC4, putative

RPB12

0.0059

PVP01_0515500

U3 small nucleolar ribonucleoprotein protein IMP4, putative

IMP4

0.0081

PVP01_0811500

proteasome subunit beta type-5, putative

 

0.0064

PVP01_1302200

high mobility group protein B1, putative

HMGB1

0.0104

PVP01_1429700

ATP-dependent RNA helicase DBP1, putative

DBP1

<0.0001

PVP01_1207600

nucleoside transporter 1

NT1

0.0001

PVP01_1432600

proline–tRNA ligase, putative

PRS

0.0406

PVP01_1022800

stearoyl-CoA desaturase, putative

SCD

0.0001

PVP01_1266000

cytoplasmic tRNA 2-thiolation protein 2, putative

NCS2

0.0431

PVP01_0825400

RING finger protein RNF1, putative

 

<0.0001

PVP01_0504400

sporozoite invasion-associated protein 2, putative

SIAP2

0.0025

  1. This table represents differentially expressed genes (RPMI, 0 h vs. RPMI 4 h, 37 °C) with exclusion of unannotated genes.
  2. Refer to Supplemental Data S3 for complete data set.
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