Table 4 Genes with annotations most highly up-regulated and down-regulated in P. vivax infected and uninfected Anopheles dirus mosquitoes.

From: Unraveling the Plasmodium vivax sporozoite transcriptional journey from mosquito vector to human host

Gene ID

Product description

Gene symbol

Assigned group

p -value

Up-regulated:

ADIR00790

alpha-crystallin B chain

alpha-crystallin B chain

Apoptosis inhibitor

<0.0001

ADIR007941

unknown function/alpha-crystallin B chain

alpha-crystallin B chain

0.0001

ADIR010798

defensin anti-microbial peptide

defensin

Immunity

<0.0001

ADIR006825

gambicin anti-microbial peptide

gambicin

<0.0001

ADIR014587

attacin anti-microbial peptide

attacin

0.0016

ADIR003751

C-type lectin

CTL

0.0004

ADIR007855

leucine-rich immune protein (Long)

LRIM

0.0004

ADIR008083

leucine-rich immune protein (Long)

LRIM

0.0026

ADIR003752

C-Type Lectin

CTL

0.0001

ADIR005185

SP14D1

SP14D1

<0.0001

ADIR007695

serine protease SP24D

SP24D

0.0207

ADIR002798

CLIP-domain serine protease

CLIPs

<0.0001

ADIR000960

peptidoglycan-recognition protein

PGRP

0.0001

ADIR007771

ficolin A

ficolin A

0.0016

ADIR006371

trehalose 6-phosphate phosphatase

T6P

Protein Catabolism

0.0001

ADIR011634

flavin-containing monooxygenase

FMO

<0.0001

ADIR008936

diamine acetyltransferase

DAT

<0.0001

ADIR003836

cysteine dioxygenase

CDO

<0.0001

ADIR008493

threonine dehydratase

TDH

0.0010

ADIR001408

4a-hydroxytetrahydrobiopterin dehydratase

OH-BH

0.0379

ADIR007539

phenylalanine-4-hydroxylase

PAH

0.0023

ADIR003591

peritrophin

peritrophin

Structural

0.0152

ADIR010042

odorant binding protein

OBP

Olfaction

0.0168

ADIR002153

pacifastin-related peptide

 

Unknown

0.0025

Down-regulated:

ADIR014650

salivary gland protein

SGP

Salivary gland enzyme

0.0062

ADIR007445

alpha-amylase

AA

0.0002

ADIR003224

salivary gland protein

SGP

0.0002

ADIR004887

23.4 kDa salivary protein

SGP

0.0215

ADIR001653

duplex-specific nuclease

DSN

DNA repair

<0.0001

ADIR000534

protein disulfide-isomerase

PDI

Protein synthesis

0.0431

ADIR003326

translation initiation factor 1 A

eIF-1a

0.0411

ADIR002569

alpha-tocopherol transfer protein-like protein

TTPAL

0.0311

ADIR004227

eukaryotic translation initiation factor 3 subunit E

eIF-3E

0.0215

ADIR001129

elongation factor 1-gamma

EF1G

0.0116

ADIR004002

dolichyl-diphosphooligosaccharide–protein glycosyltransferase subunit 1

DDOST

0.0122

ADIR009737

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase

GalNAc-T

0.0112

ADIR003797

eukaryotic translation initiation factor 3 subunit L

eIF-3L

0.0011

ADIR001338

small ubiquitin-related modifier

SUMO

0.0296

ADIR000499

translocase of outer mitochondrial membrane 20 homolog

TOMM20

0.0054

ADIR009264

alpha-12C2-Mannosidase

MAN12C2

0.0362

ADIR009439

carboxylic ester hydrolase

CEH

Protein catabolism

0.0019

ADIR010119

carboxylic ester hydrolase

CEH

<0.0001

ADIR010296

serine incorporator

SERINC

Transporter

0.0109

ADIR009494

V-type proton ATPase proteolipid subunit

V-ATPase

0.0165

ADIR006128

+V-type H+-transporting ATPase 21kDa proteolipid subunit

V-ATPase

0.0107

ADIR004742

proton-coupled amino acid transporter

PAT

0.0007

ADIR006703

sodium-independent sulfate anion transporter

SLC

0.0007

ADIR004547

V-type H+-transporting ATPase subunit E

V-ATPase

0.0148

ADIR010593

V-type proton ATPase catalytic subunit A

V-ATPase

0.0245

ADIR000034

solute carrier family 15 member

SLC15

0.0196

ADIR008886

signal recognition particle subunit SRP54

SRP54

Immunity

0.0046

ADIR007705

C-type lectin

CTL

0.0161

  1. The table represents differentially expressed genes of infected vs. uninfected salivary glands with exclusion of unannotated genes.
  2. Refer to Supplemental Data S9 and S10 for complete data sets.
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