Table 1 Size distribution parameters of the obtained spray-dried MP and commercial powders.

From: In vitro performances of novel co-spray-dried azithromycin/rifampicin microparticles for Rhodococcus equi disease treatment

 

NMD (µm) ± S.D.

Span

VMD (µm) ± S.D.

Span

AZM MP

1.8 ± 0.5

2.46

60.8 ± 6.8

1.15

RIF MP

2.8 ± 0.8

4.54

137.2 ± 10.5

2.51

AZM/RIF MP 1:1

2.9 ± 0.9

3.81

87.9 ± 5.7

1.32

AZM/RIF MP 2:1

2.4 ± 0.7

2.98

56.5 ± 5.3

1.19

AZM/RIF MP 1:2

4.8 ± 1.2

5.90

91.3 ± 10.2

3.04

RIF powder

10.9 ± 2.3

20.59

111.1 ± 12.8

3.31

AZM powder

10.3 ± 1.9

3.50

150.2 ± 15.4

4.55

  1. Results are mean ± S.D. Broadness of size distribution (span) was calculated using equation 1.
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