Table 3 Extracellular antimicrobial activity of the microparticle formulations against R. equi ATCC 33701.

From: In vitro performances of novel co-spray-dried azithromycin/rifampicin microparticles for Rhodococcus equi disease treatment

 

MIC

(mg/L)

FICI

MBC (mg/L)

FBCI

AZM MP

0.5

—

8

—

RIF MP

0.125

—

16

—

AZM/RIF MP 1:1

0.06/0.06

0.6

1/1

0.19

AZM/RIF MP 2:1

0.125/0.06

0.73

2/1

0.31

AZM/RIF MP 1:2

0.03/0.06

0.54

1/2

0.25

  1. The values of FICI and FBCI depend on the calculation model of Equation 3.