Figure 1
From: Structural basis for polymerase η–promoted resistance to the anticancer nucleoside analog cytarabine
Deoxycytidine, cytarabine, and cytidine nucleosides. Chemical structures of 2′-deoxycytidine (dC, 1-β-D-2′-deoxy-ribofuranosylcytosine), cytarabine (AraC, 1-β-D-arabinofuranosylcytosine), and cytidine (C, 1-β-D-ribofuranosylcytosine). The 2′-OH group in arabinose and ribose sugar moieties points in opposite directions.
