Figure 2 | Scientific Reports

Figure 2

From: AAV serotype 8-mediated liver specific GNMT expression delays progression of hepatocellular carcinoma and prevents carbon tetrachloride-induced liver damage

Figure 2

Evaluation of liver injury in AAV8-injected Gnmt−/− mice. (a) Levels of GNMT and pro-inflammatory genes including TNF-α, IL-6 and F4/80 were measured by qPCR. *p < 0.05. (b) Serum levels of TNF-α and IL-6 were detected by ELISA analysis. *p < 0.05. (c) Body weight and (d) the values of serum biochemistry including ALT, AST, triglyceride and cholesterol were examined at indicated time points. *p < 0.05 when KO-AAV8-GNMT group is compared with KO-AAV8-eGFP. #p < 0.05 when KO-AAV8-GNMT group is compared with KO.

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