Figure 2
From: Low dose of chlorine exposure exacerbates nasal and pulmonary allergic inflammation in mice
Timeline of the experimental protocol. On days 0 and 14 mice of OVA, OVA +3.3 Cl2, OVA + 33.3 Cl2 received intraperitoneal (I.P.) injections of OVA solution with vehicle, while the SAL group received only vehicle (open triangles). Aerosol challenges with a 1% OVA solution were performed four times on days 22, 24, 26, and 28 (closed triangles) and animals in the SAL group received only aerosolized saline. A single Cl2 exposure was performed on day 29 (closed circle). After Cl2 exposure, lung mechanics were measured, and the animals were euthanized.
