Figure 3 | Scientific Reports

Figure 3

From: In vivo imaging of bacterial colonization of the lower respiratory tract in a baboon model of Bordetella pertussis infection and transmission

Figure 3

Clinical symptoms of pertussis developed by naive animals co-housed with baboons infected with B. pertussis. Nasopharyngeal B. pertussis colonization for K921A (red) and K937B (green) (A) was estimated by swab plating on Bordet-Gengou blood agar plates. Circulating white blood cell numbers (B) were also measured over time. The dotted line corresponds to estimated pathological WBC counts. Fluorescence of recovered nasopharyngeal B. pertussis was assessed by confocal fluorescence imaging as soon as bacteria were first detected in swabs at D9 for K921A (C) and D20 for K937B (D). All bacteria were detected in grey by transmitted light microscopy and GFP expressing B. pertussis were detected in green (arrows) by confocal fluorescence microscopy. Scale bar: 2 μm.

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