Figure 6
From: PSD-95-nNOS Coupling Regulates Contextual Fear Extinction in the Dorsal CA3
The role of PSD-95-nNOS in regulating contextual fear extinction is BDNF-dependent. (A) Design of the experiments for (B–D). (B) BDNF scavenger TrkB-FC reversed the effect of LV-nNOS1–133-GFP on fear extinction (n = 13). (C) BDNF scavenger TrkB-FC reversed the effect of LV-nNOS1–133-GFP on BDNF expression (n = 4–5). (D) TrkB receptor antagonist ANA-12 reversed the effect of LV-nNOS1–133-GFP on fear extinction (n = 11).
