Figure 1 | Scientific Reports

Figure 1

From: Regional variations in stiffness in live mouse brain tissue determined by depth-controlled indentation mapping

Figure 1

(a) Microscope image of one of the slices used in this experiment, along with a typical 50 × 50 μm indentation grid (red dots). Dashed lines indicate boundaries of morphologically distinct anatomical regions. Abbreviations: Sub - subiculum, SLM - stratum lacunosum moleculare, SR - stratum radiatum, SP - stratum pyramidale, SO - stratum oriens, ML - molecular layer, GCL - granule cell layer; large regions: DG - dentate gyrus, CA - cornus ammonis. (b,c) Color-coded map of storage E′ (b) and loss modulus E″ (c) in Pa over the DG and CA3 field of the hippocampal formation obtained with oscillatory ramp depth-controlled indentation strokes (see Methods) with 0.2 μm oscillation amplitude, 5.62 Hz oscillation frequency, and 9% strain. Gray color indicates failed measurements.

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