Figure 3 | Scientific Reports

Figure 3

From: Evaluation of modified Interferon alpha mRNA constructs for the treatment of non-melanoma skin cancer

Figure 3

Biolistic eGFP IVT mRNA transfection in human skin explants. (a,h–l) Untransfected control biopsies. (b–g) Biopsies treated biolistically with 1 μg/μl eGFP mRNA. Reactivity for eGFP (green), F-Actin (red) and nuclei (blue) as indicated. (b) Additional suprabasal GFP-transfected cells are marked by white arrowheads. (g) Gold particles are visible in merged fluorescence + bright field image after biolistic eGFP mRNA delivery. Scale bars in (a,b) represent 500 μm; Scale bars in (c–l) represent 50 μm.

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