Figure 2 | Scientific Reports

Figure 2

From: Lysogenization of Staphylococcus aureus RN450 by phages ϕ11 and ϕ80α leads to the activation of the SigB regulon

Figure 2

Effects of lysogenization on the transcriptome of S. aureus RN450. (A) KEGG pathway analysis of genes up- (red) and down-regulated (blue) in both lysogenic strains compared to the non-lysogenic strain. Bars indicate the number of genes belonging to those pathways that changed in both lysogenic strains. (B) Overlap of genes dysregulated in both lysogens with the SigB and CcpA regulons. Green nodes represent regulators SigB and CcpA, which did not show changes in gene expression in the RNA-seq analysis. Red and blue nodes represent up- and down-regulated genes identified by RNA-seq analysis, respectively. Red and blue arrows represent a positive and negative effect on the expression of another gene, respectively.

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