Table 4 Genotype association with optical coherence tomography (OCT)-derived drusen volume in participants with AMD (n = 347).
Number (%) with Drusen volume = 0 | Number (%) with Drusen volume > 0 | Model 1* | Model 2* | |||
|---|---|---|---|---|---|---|
OR (95% CI) | P_val | OR (95% CI) | P_val | |||
CFH rs900292 | 0.82 (0.58 1.16) | 0.251 | 0.78 (0.53 1.14) | 0.203 | ||
CC | 71(54.62%) | 59(45.38%) | ||||
AC | 104(61.9%) | 64(38.1%) | ||||
AA | 29(59.18%) | 20(40.82%) | ||||
ARMS2 rs10490924 | 1.59 (1.14 2.24) | 0.007 | 1.54 (1.08 2.19) | 0.017 | ||
GG | 83(68.6%) | 38(31.4%) | ||||
GT | 96(58.18%) | 69(41.82%) | ||||
TT | 25(40.98%) | 36(59.02%) | ||||
CETP rs3764261 | 0.97 (0.66 1.42) | 0.864 | 0.97 (0.65 1.45) | 0.885 | ||
CC | 130(59.09%) | 90(40.91%) | ||||
AC | 62(56.36%) | 48(43.64%) | ||||
AA | 12(70.59%) | 5(29.41%) | ||||
D442G rs2303790 | NA | NA | NA | NA | ||
TT | 203(58.67%) | 143(41.33%) | ||||
GT | 1(100%) | 0(0%) | ||||
GG | 0 | 0 | ||||
