Figure 9
Correlation of TFAM expression with invasive and mitochondrial biogenesis signatures. Correlation analysis showed a negative correlation of TFAM expression with invasive signature in both melanoma cell lines (r = −0.55; p = 0.034) (A) and TCGA metastatic melanoma samples (r = −0.12; p = 0.019) (C). TFAM expression was also positive correlated with mitochondrial biogenesis in both cell lines (r = 0.82; p = 0.00017) (B) and TCGA data (r = 0.4; p = 2.9 × 10−15) (D).
