Table 1 Classification of autoimmune hyperthyroidism and Graves’ orbitopathy in male versus female GO mouse model.
From: Graves’ orbitopathy occurs sex-independently in an autoimmune hyperthyroid mouse model
Disease classification | Z-Score | Males | Females | ||
|---|---|---|---|---|---|
No | % | No | % | ||
Autoimmune hyperthyroidism | |||||
Subclinical | ≤0 | 4 | 28.6 | 3 | 21.4 |
Clinical | >0 | 10 | 71.4 | 11 | 78.6 |
Mild | >0–1 | 7 | 50.0 | 4 | 28.5 |
Moderate-to-severe | >1 | 3 | 21.4 | 5 | 35.7 |
Graves’ orbitopathy MRI | |||||
Subclinical | ≤0 | 2 | 33.3 | 1 | 20.0 |
Clinical | >1 | 4 | 66.7 | 4 | 80.0 |
Mild | >0–1 | 3 | 50.0 | 3 | 60.0 |
Moderate-to-severe | >1 | 1 | 16.7 | 1 | 20.0 |
Graves’ orbitopathy Histology | |||||
Subclinical | ≤0 | 5 | 35.7 | 4 | 28.6 |
Clinical | >0 | 9 | 64.3 | 10 | 71.4 |
Mild | >0–1 | 8 | 57.1 | 7 | 50.0 |
Moderate-to-severe | >1 | 1 | 14.3 | 3 | 21.4 |
