Table 6 Comparisons of the vascular density, perfusion density, and foveal avascular zone metrics between two consecutive macular angiography scans showing different signal strength in the same subjects (n = 17).

From: The Importance of Signal Strength in Quantitative Assessment of Retinal Vessel Density Using Optical Coherence Tomography Angiography

 

1st measurements Signal strength = 8

2nd measurements Signal strength = 9

p-value

Vessel density

  Total area (mean ± SD, mm−1)

15.31 ± 2.13

16.64 ± 1.29

 < 0.001

  Center (mean ± SD, mm−1)

6.87 ± 3.05

7.91 ± 2.32

0.031

  Inner - average (mean ± SD, mm−1)

14.99 ± 2.63

16.31 ± 2.22

0.010

  Outer - average (mean ± SD, mm−1)

15.72 ± 2.09

17.06 ± 1.20

 < 0.001

Perfusion density

  Total area (mean ± SD)

0.380 ± 0.054

0.414 ± 0.033

0.001

  Center (mean ± SD)

0.149 ± 0.072

0.173 ± 0.054

0.025

  Inner - average (mean ± SD)

0.349 ± 0.069

0.382 ± 0.058

0.012

  Outer - average (mean ± SD)

0.380 ± 0.054

0.414 ± 0.033

 < 0.001

Foveal avascular area

  Area (mean ± SD, mm2)

0.18 ± 0.09

0.22 ± 0.10

0.042

  Perimeter (mean ± SD, mm)

1.83 ± 0.42

1.91 ± 0.41

0.118

  Circularity (mean ± SD)

0.67 ± 0.09

0.72 ± 0.08

0.046

  1. SD, standard deviation.
  2. The p-value was obtained using a Wilcoxon signed rank test.
  3. Boldface numbers indicate statistically significant differences at p < 0.05.
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