Table 1 Baseline characteristics of Ankylosing Spondylitis patients with active and inactive disease and healthy controls.
All AS (n = 54) | Inactive (n = 17) | Active (n = 37) | P value Active vs Inactive | Healthy controls (n = 28) | P value AS vs Healthy controls | |
|---|---|---|---|---|---|---|
Age, years | 40.0 (34–48) | 41.0 (35–47) | 40.0 (31–48) | 0.79 | 43.5 (39–48) | 0.24 |
Male, % | 66.7 | 76.5 | 62.2 | 0.30 | 46.4 | 0.08 |
Body Mass Index | 26.7 (22.3–29.3) | 27.1 (22.8–30.0) | 26.4 (22.0–28.9) | 0.51 | 26.4 (24.4–28.9) | 0.62 |
Smoking, % | 20.4 | 17.7 | 21.6 | 1 | 17.9 | 0.79 |
Hypercholesterolemia,% | 68.5 | 82.4 | 62.1 | 0.21 | 85.7 | 0.09 |
Hypertension, % | 13.0 | 11.8 | 13.5 | 1 | 0 | 0.09 |
Disease duration, years | 6.5 (2.0–12.5) | 7.0 (3.0–12.0) | 6.0 (2.0–13.0) | 0.54 | — | — |
BASDAI | 6.2 (3.8–7.2) | 2.0 (1.6–3.2) | 6.7 (6.0–7.7) | <0.001 | — | — |
VAS pain | 64.0 (35.0–74.0) | 23.0 (8.0–35.0) | 70.0 (62.0–78.0) | <0.001 | — | — |
ASDAS – CRP | 3.5 (2.0–4.2) | 1.4 (1.0–1.9) | 3.8 (3.4–4.3) | <0.001 | — | — |
ASDAS - ESR | 3.3 (1.9–3.6) | 1.4 (0.8–1.9) | 3.4 (3.2–4.0) | <0.001 | — | — |
CRP, mg/dl | 8.0 (3.2–14) | 3.3 (1.8–4.3) | 9.7 (6.1–20.6) | <0.001 | 1.4 (0.8–2.5) | <0.001 |
ESR, mm/h | 12.1 (6.1–22.3) | 6.1 (3.0–10.3) | 17.4 (9.0–26.6) | 0.002 | — | — |