Table 1 Baseline characteristics of Ankylosing Spondylitis patients with active and inactive disease and healthy controls.

From: Microvascular dysfunction in ankylosing spondylitis is associated with disease activity and is improved by anti-TNF treatment

 

All AS (n = 54)

Inactive (n = 17)

Active (n = 37)

P value Active vs Inactive

Healthy controls (n = 28)

P value AS vs Healthy controls

Age, years

40.0 (34–48)

41.0 (35–47)

40.0 (31–48)

0.79

43.5 (39–48)

0.24

Male, %

66.7

76.5

62.2

0.30

46.4

0.08

Body Mass Index

26.7 (22.3–29.3)

27.1 (22.8–30.0)

26.4 (22.0–28.9)

0.51

26.4 (24.4–28.9)

0.62

Smoking, %

20.4

17.7

21.6

1

17.9

0.79

Hypercholesterolemia,%

68.5

82.4

62.1

0.21

85.7

0.09

Hypertension, %

13.0

11.8

13.5

1

0

0.09

Disease duration, years

6.5 (2.0–12.5)

7.0 (3.0–12.0)

6.0 (2.0–13.0)

0.54

BASDAI

6.2 (3.8–7.2)

2.0 (1.6–3.2)

6.7 (6.0–7.7)

<0.001

VAS pain

64.0 (35.0–74.0)

23.0 (8.0–35.0)

70.0 (62.0–78.0)

<0.001

ASDAS – CRP

3.5 (2.0–4.2)

1.4 (1.0–1.9)

3.8 (3.4–4.3)

<0.001

ASDAS - ESR

3.3 (1.9–3.6)

1.4 (0.8–1.9)

3.4 (3.2–4.0)

<0.001

CRP, mg/dl

8.0 (3.2–14)

3.3 (1.8–4.3)

9.7 (6.1–20.6)

<0.001

1.4 (0.8–2.5)

<0.001

ESR, mm/h

12.1 (6.1–22.3)

6.1 (3.0–10.3)

17.4 (9.0–26.6)

0.002

  1. Data are median (IQR). Mann-Whitney U test was used for comparing continuous variables. Chi-square test or Fisher exact test were used for dichotomous variables. AS – Ankylosing Spondylitis.