Figure 4

Survival faction vs. cumulative equivalent minutes (CEM43). (a) MiaPaCa-2 cells and (b) L929 cells: Survival fraction substantially drops for MFH-treated cells at a CEM43 of approx. [1, 10] min. For hotplate hyperthermia treated cells the same substantial drop is observed at a CEM43 of approx. 50 min and above. Note that intracellular ML samples for the L929 cells are not shown here, as only samples showing significant damage caused by MFH were regarded (cf. Fig. 2d).